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However, Prospective data from the Level 1 MI programme were analysed.
All STEMI patients presenting to the Minneapolis Heart Institute or 31 referral hospitals received aspirin, clopidogrel, and unfractionated heparin (UFH) at the presenting hospital and those presenting to hospitals ≥60 miles away also received half-dose fibrinolytic with transfer for immediate PCI.
A standardized protocol with pre-printed standing orders was implemented at each hospital.
Each patient received aspirin 325 mg p.o., clopidogrel 600 mg p.o., unfractionated heparin (UFH) 60 U/kg i.v. infusion (max 1000 U/h), and a beta-blocker (unless contraindicated) in the emergency department at the presenting hospital.
To determine the safety and efficacy of a pharmaco-invasive reperfusion strategy utilizing half-dose fibrinolysis combined with transfer for immediate percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI) patients presenting to remote rural hospitals.
Percutaneous coronary intervention Hosp: (Minneapolis Heart Institute at Abbott Northwestern Hospital).
We also compared patients receiving primary PCI at both the PCI hospital and Zone 1 (Group A B) with those receiving a pharmaco-invasive approach (Group C D) in both Zone 1 and Zone 2.
Categorical variables are reported as the number of patients (%) with the characteristic, except for door-to-balloon and length of stay (LOS) values which are reported as the median, and the 25 and 75th percentiles.
5.6%; Within a regional STEMI system of care, half-dose fibrinolysis combined with immediate transfer for PCI may be a safe and effective option for STEMI patients with expected delays due to long-distance transfer.
The optimal reperfusion strategy for ST-segment elevation myocardial infarction (STEMI) is primary percutaneous coronary intervention (PCI) if it can be performed in a timely manner by experienced providers.
A nearest-neighbour 1:1 matching algorithm was used to match subjects on the basis of the logit of the propensity score.